6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER - Names and Identifiers

Name	1H-Indazole-4-carboxylicacid, 6-bromo-, methyl ester
Synonyms	Methyl 6-bromo-(1H)-indaz... methyl 6-bromo-1H-indazole-4-carboxylate 6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 6-bromo-4-Indazolecarboxylic acid methyl ester 6-BroMo-1H-indazol-4-carboxylic acid Methyl ester 6-BroMo-1H-indazole-4-carboxylic acid Methyl ester 1H-Indazole-4-carboxylicacid, 6-bromo-, methyl ester 1H-Indazole-4-carboxylic acid, 6-broMo-, Methyl ester
CAS	885518-49-0
InChIKey	FEPRHRPOKPTRQZ-UHFFFAOYSA-N

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER - Physico-chemical Properties

Molecular Formula	C9H7BrN2O2
Molar Mass	255.07
Density	1.709±0.06 g/cm3(Predicted)
Boling Point	395.9±22.0 °C(Predicted)
pKa	11.21±0.40(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Use	This product is for scientific research only and shall not be used for other purposes.

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER - Introduction

6-bromo-, methyl ester is an organic compound containing an indazole structure with the chemical formula C10H8BrN3O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-melting point: about 144-146 ℃
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide

Use:
6-bromo-, methyl ester is an important intermediate, commonly used in organic synthesis, can be used to prepare a variety of indazole compounds, such as drugs, dyes and so on.

Preparation Method:
6-bromo-, methyl ester can be synthesized by the following steps:
1. First, 4-indazole carboxylic acid and bromine are reacted in the presence of sodium hydride to obtain 6-bromo-4-indazole carboxylic acid. Br> 2. then, 6-bromo -4-indazole carboxylic acid is reacted with methanol in the presence of potassium carbonate to generate 6-bromo-, methyl ester.

Safety Information:
-, 6-bromo-, methyl ester is a chemical that requires personal protective measures when used.
-It may be irritating and corrosive to the skin, eyes and respiratory tract, so avoid contact with skin, eyes and intake during use.
-The operation needs to be carried out in a well-ventilated place and equipped with suitable protective equipment, such as gloves, goggles and protective clothing.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-In handling and storage, should follow the relevant safety procedures, away from the fire and flammable materials.

Last Update：2024-04-09 21:01:54